BDBM50363397 CHEMBL1946170::REGORAFENIB::US10183928, Regorafenib::US10202365, Compound Regorafenib::US10227329, Compound Regorafenib::US10464902, Regorafenib::US10584114, Compound Regorafenib::US10774070, Compound Regorafenib::US11279688, Compound Regorafenib

SMILES CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)c(F)c2)ccn1

InChI Key InChIKey=FNHKPVJBJVTLMP-UHFFFAOYSA-N

Data  1 KI  46 IC50  1 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50363397   

TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50363397(CHEMBL1946170 | REGORAFENIB | US10183928, Regorafe...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of PDGFR beta (561 to 1106 residues) (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank